Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA6792 | CA33657 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | IDV | 104 |
| 2 | 3TC+D4T+IDV | 57 |
| 3 | D4T+EFV+RTV+SQV | 30 |
| 4 | 3TC+D4T+NFV+NVP | 52 |
| 5 | ABC+D4T+DLV+SQV | 34 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46I, I54V, V82A, L90M | F53L | K20R, M36I, L63P, A71V, I93L |
| >CA33657| codons 1-99 PQITLWQRPLVTIKIGGQLREALLDTGADDTILEEINLPGRWKPKIIGGIGGLVKVRQYD QIPIEICGHKVIGTVLVGPTPANIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67DN, T215Y | K103N | T39A, K122E, I135V, I142V, A272S, K277R, Q278E, I293V, E297K | Y232H |
| >CA34673| codons 1-299 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICAELEKEGKISKIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSVNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFYTPDKKHQKEPPFLWMGHELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVRELCKLLRGTKALTEVVPLTKEA |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |