Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA5110 | CA33644 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT | 157 |
| 2 | D4T+DDI+EFV | 35 |
| 3 | ABC+D4T+IDV+RTV | 17 |
| 4 | ABC+D4T+NFV | 108 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N, M46MI | N88ND | L10V, T12I, I15V, E35D, N37D, A71AV |
| >CA33644| codons 1-99 PQITLWQRPVVIIKVGGQLKEALLDTGADNTVLEDMDLPGRWKPKIIGGIGGFIKVRQYD QILIEICGHKVIGTVLVGPTPVNIIGRDLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L210LW, T215Y | K103N | K20R, T39TA, V60I, D123E, I135T, I142V, Q207A, R211K, L228LR, D250E, A272P, K277R, T286A, I293V, E297K |
| >CA34663| codons 1-302 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICAELEKEGKISKIGPENPYNTPI FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRAHLWKWGFYTPDKKHQKEPPFRWMGYELHPDKWT VQPIVLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEVVPLTKEAE LE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |