Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA5294 | CA33634 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T | 7 |
| 2 | NRTI | 106 |
| 3 | 3TC+D4T+IDV | 52 |
| 4 | IDV | 8 |
| 5 | None | 5 |
| 6 | 3TC+AZT+NVP | 40 |
| 7 | 3TC+ABC+AZT+NVP | 67 |
| 8 | Unknown | 9 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A | L24I | Q7D, L10I, I15V, L19I, E35D, N37T, R41K, I62IV, L63P, A71V |
| >CA33634| codons 1-99 PQITLWDRPIVTIKVGGQIKEALIDTGADDTVLEDMTLPGKWKPKMIGGIGGFVKVRQYD QVPIEICGHKVIGTVLVGPTPANIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | Y181YC, G190GA | K20R, D123E, I135R, I142IV, S162C, D177E, V189VI, E203D, R211K, V245M, A272P, T286A, I293IV, E297A |
| >CA34650| codons 1-301 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSRNNETPGVRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPEIVI CQYVDDLYIASDLEIGQHRTKIDELRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIMLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVVPLTAEAE L |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |