<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CA7897 CA33607 U.S. 2002 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 AZT+DDI 113
2 3TC+AZT 18
3 D4T+DDC+IDV 218
4 APV+DDI+NVP 48
5 3TC+DDI+LPV+NVP+TDF 36

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82A L24I, L33F L10I, E34EQ, M36ML, N37ND, R41RK, K55R, R57RK, I62V, L63P, A71T, I72T  
>CA33607| codons 1-99
PQITLWQRPIVTIKIGGQLKEALIDTGADDTVFQELDLPGKWKPKLIGGIGGFVRVKQYD
QVPIEICGHKTTGTVLVGPTPANIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70KR, M184V, T215F K219E K101E, Y181C, G190A   N175NH, I202V, H208Y, R211K, L228LH, V245E, A272AP  
>CA34624| codons 1-301
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQHPDIVI
CQYVDDLYVASDLEIGQHRTKVEELRQYLLKWGFFTPDEKHQKEPPFHWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTEEAE
L

References
Author Title Citation
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005