Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA7971 | CA33593 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+3TC+NFV | 74 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46ML | L19Q, A71T, V77I |
| >CA33593| codons 1-99 PQITLWQRPLVTIKIGGQQKEALLDTGADDTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD QILIEICGHKTIGTVLIGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | A62AV | E6EG, R83K, K103R, D123E, S162C, D177E, T200A, P243S, V245E, A272P, K281R, T286A, V292I, I293V, M357T, R358RK, T369V, A376T, T386S, E399D, A400T, Y405H, A446S, D460N, R461K, S468T, H483Y, Q509I, Q520R, Q524E, A554N |
| >CA34609| codons 1-560 PISPIGTVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FVIKKKDSTKWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKRKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQSIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTEIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLKTGKYARTKGA HTNDVKQLVEAVQKITTESIVIWGKSPKFKLPIQKETWDTWWTEHWQATWIPEWEFVNTP PLVKLWYQLEKEPIVGAETFYVDGASNRETKLGKAGYVTNKGRQKVVTLTDTTNQKTELQ AIYLALQDSGLEVNIVTDSQYALGIIQAIPDKSESELVSRIIEELIKKEKVYLAWVPAHK GIGGNEQVDKLVSNGIRKVL |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |