<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CA5350 CA33585 U.S. 2002 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 AZT 213
2 DDI 91
3 D4T 61
4 AZT+DDC+IDV 60
5 3TC+AZT+IDV 17
6 3TC+D4T+NVP 47
7 ABC+RTV+SQV 150

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V82T, I84V, L90M V11VI, L33F, G73S L10V, I13V, I15V, N37ND, K45R, I62IV, L63P, A71V  
>CA33585| codons 1-99
PQITLWQRPVITVKVGGQLKEALLDTGADDTVFEEMDLPGRWKPRMIGGIGGFIKVRQYD
QVPIEICGHKVISTVLVGPTPTNVIGRNLMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70GR, T215F K219Q     V35T, T39A, V60I, T69N, K122E, I135T, T139M, I178IL, G196E, E203ED, H208HY  
>CA34600| codons 1-252
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICAELEKEGKISKIGPENPYNTPI
FAIKKKNSNGWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSTNNEMPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDLVI
YQYMDDLYVGSDLEIEQHRTKIDELRQYLLRWGFFTPDQKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSW

References
Author Title Citation
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005