<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
4245 13.ZA.GT3041 South Africa 2013 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+EFV+TDF NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
T69D, M184V   K101E, V106M, G190A F227L K20R, V35T, T39E, V60I, L109I, K122E, D123K, K173T, Q197R, T200A, Q207A, L228R, V245Q  
>13.ZA.GT3041| codons 1-257
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICEEMEKEGKISKIGPENPYNTPI
FAIKKKDSDKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSMTVIDVGDAYFSVPL
DEKFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTQNPDIVI
YQYVDDLYVASDLEIGRHRAKIEELRAHLLRWGFTTPDKKHQKEPPLRWMGYELHPDKWT
VQPIQLPEKDSWTVNDI

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19V, E35D, M36I, R41K, L63V, H69K, T74S, L89M, I93L  
>13.ZA.GT3041| codons 1-99
PQITLWQRPLVSIKVGGQVKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QIVIEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Neogi, U Mutational Heterogeneity in p6 Gag Late Assembly (L) Domains in HIV-1 Subtype C Viruses from South Africa. ARHR, 2016