Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA14311 | CA33502 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI | 169 |
| 2 | 3TC+D4T+NVP | 96 |
| 3 | 3TC+APV+D4T | 130 |
| 4 | 3TC+APV+D4T+DDC | 32 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I84V, L90M | I13IV, L19Q, K20M, I62V, L63P, A71AT, I72IT |
| >CA33502| codons 1-99 PQITLWQRPLVTVKIGGQQMEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVRQYD QVPIEICGHKTTGTVLVGPTPVNVIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T69D, K70R, M184V, T215F | D67G, K219Q | Y181YC, G190A | E6D, S68G, K101Q, K102R, K122E, I135T, I142IV, Q207R, R211Q, D218DE, R284K, I293V, E297EV |
| >CA34518| codons 1-301 PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKGGDRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLQRKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI CQYVDDLYVASDLEIGQHRTKIEELRRHLLQWGFFTPEQKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLKGTKALTEVVPLTVEAE L |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |