Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA14297 | CA33484 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 48 |
| 2 | 3TC+AZT | 22 |
| 3 | 3TC+AZT+IDV | 52 |
| 4 | 3TC+DDC+NFV | 31 |
| 5 | D4T+DDI+DLV | 78 |
| 6 | ABC+APV+D4T+DDI | 140 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54L | K43T | L10I, I15V, K20E, E34K, E35D, M36I, I62T, L63P, A71V, I93L |
| >CA33484| codons 1-99 PQITLWQRPIVTIKVGGQLEEALLDTGADDTVLKDINLPGRWTPKMIGGIGGFLKVRQYD QTPIEICGHKVIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L210W, T215Y | K20R, K32E, V35VL, T39AE, E40F, K43KE, R83K, V90I, V118I, K122E, T139K, K173T, I178L, G196E, Q207E, H208Y, V245E, E297A |
| >CA34491| codons 1-300 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIEALLEICAFLEEEGKISKIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKKTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSINNEKPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTQNPDLVI YQYMDDLYVGSDLEIEQHRTKIEELREYLWRWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVIPLTAEAE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |