Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA5114 | CA33483 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+IDV | 18 |
| 2 | D4T+DDI+NFV | 44 |
| 3 | None | 70 |
| 4 | 3TC+AZT+NFV | 127 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54V, V82A | L24I | L10IV, M36MI, R41RK, Q61E, L63P, I64V, K70T, A71V, T74S, I93L |
| >CA33483| codons 1-99 PQITLWQRPIVTIKIGGQLKEALIDTGADDTVLEEINLPGKWKPKLIGGIGGFVKVRQYD EIPVEICGHTVIGSVLVGPTPANIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T69S_ST, M184V, L210LW, T215F | E44ED, V118I, I135T, T165L, E169EK, K173E, T200A, F214L, A272P, K281R, T286A, E297K |
| >CA34495| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKDGKISKIGPENPYNTPV FAIKKKDSSKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMLKILKPFREQNPDIVI YQYVDDLYVGSDLEIGQHRAKIEELRQHLWRWGLFTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTEVIPLTKEAE L |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |