Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1313 | CA33420 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 104 |
| 2 | 3TC+AZT | 52 |
| 3 | AZT+DDI+SQV | 30 |
| 4 | 3TC+D4T+NFV | 25 |
| 5 | 3TC+D4T+NVP+IDV | 46 |
| 6 | 3TC+D4T+IDV | 204 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L90M | L10I, K20I, D60E, I62V, L63P, H69HY, A71T, I72E, G73X, V77I, I93L |
| >CA33420| codons 1-99 PQITLWQRPIVTIKIGGQLIEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVRQYE QVPIEICGYKTEXTVLIGPTPVNIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, M184V, L210W, T215Y | M16MV, K20R, T39A, K49KR, V60I, R83K, V90VI, V118VI, K122KE, I135T, S162X, E169D, G196E, I202V, Q207E, R211K, A272P, I293V |
| >CA34436| codons 1-301 PISPIETVPVKLKPGVDGPRVKQWPLTEEKIKALVEICAELEKEGKISRIGPENPYNTPI FAIKKKNSDKWRKLVDFRELNKKTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQXSMTKILDPFRKQNPDIVI YQYVDDLYVGSDLEIEQHRTKVEELREHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVVPLTEEAE L |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |