Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA9777 | CA33416 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC | 165 |
| 2 | D4T+DDI+RTV+SQV | 52 |
| 3 | 3TC+ABC+APV+DLV+EFV+IDV | 52 |
| 4 | 3TC+ABC+APV+RTV | 17 |
| 5 | None | 53 |
| 6 | 3TC+ABC+APV+RTV | 22 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54M, V82A, L90M | L33F | L10I, I13V, K14R, I15V, D60E, I62V, L63P, C67E, A71AV, I72V, V77I |
| >CA33416| codons 1-99 PQITLWQRPIVTVRVGGQLKEALLDTGADDTVFEEMNLPGRWKPKMIGGIGGFMKVRQYE QVPIEIEGHKVVGTVLIGPTPANIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74V, M184V, L210W, T215Y | K219R | K20R, T39A, K43E, V118I, S162C, E169D, D177E, G196E, E203K, Q207E, R211K, K223E, L228R, V245E, A272P, E297T | K126P |
| >CA34432| codons 1-300 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICAELEEEGKISKIGPENPYNTPV FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DKDFRPYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFRKQNPEIVI YQYVDDLYVGSDLEIEQHRTKIKELREHLWKWGFYTPDRKHQEEPPFRWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTEVIPLTTEAE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |