Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA14233 | CA33365 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDI+SQV | 104 |
| 2 | 3TC+D4T | 31 |
| 3 | ABC+EFV+NFV+RTV | 108 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I84V, L90M | G73S | L10I, I15V, Q18QH, L19I, K20T, E35ED, M36I, L63P, I66IV, A71X, I85V |
| >CA33365| codons 1-99 PQITLWQRPIVTIKVGGHITEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVRQYD QIPIEVCGHKXISTVLVGPTPVNVVGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, L74LI, M184V | T215I, K219E | K103N | L234LI | E6D, V60I, V90VI, V108X, K122E, D123N, I142V, Q174QR, I202V, Q207E, L228R, A272P, T286A, E297K |
| >CA34380| codons 1-300 PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPI FAIKKKNSTRWRKIVDFRELNKRTQDFWEIQLGIPHPAGLKKNKSVTXLDVGDAYFSVPL DENFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKRNPDIVI YQYVDDLYVGSDLEIGQHRTKVEELREHLLRWGFITPDEKHQKEPPFRWMGYEIHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVIPLTKEAE |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |