Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA364 | CA33351 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | SQV | 28 |
| 2 | D4T | 117 |
| 3 | 3TC+D4T+NFV | 109 |
| 4 | None | 63 |
| 5 | 3TC+D4T+NVP | 2 |
| 6 | 3TC+D4T+NFV | 64 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | I15V, K20T, E35D, M36I, N37D, I62V, L63P, I64IM, A71V, T74S, I93L |
| >CA33351| codons 1-99 PQITLWQRPLVTIKVGGQLTEALLDTGADDTVLEDIDLPGRWKPKMIGGIGGFIKVRQYD QVPMEICGHKVIGSVLVGPTPVNIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K20KR, I135V, S162C, G196GV, Q207X, R211K, E248ED, A272P, K277R, I293IV, E297K |
| >CA34366| codons 1-301 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIVQHRTKIEELRXHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVVPLTKEAE L |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |