Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA3955 | CA33338 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 67 |
| 2 | AZT+DDI | 59 |
| 3 | None | 68 |
| 4 | 3TC+D4T+IDV | 61 |
| 5 | D4T+DDI+EFV | 12 |
| 6 | D4T+DDI+EFV+NFV | 11 |
| 7 | D4T+DDI+RTV+SQV | 72 |
| 8 | APV+D4T+DDI | 63 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46IL, G48GV, V82A, I84V, L90LM | L10I, K20I, L63C, A71V, V77I, T91TS |
| >CA33338| codons 1-99 PQITLWQRPIVTIKIGGQLIEALLDTGADDTVLEEMNLPGRWKPKIIVGIGGFIKVRQYD QICIEICGHKVIGTVLIGPTPANVIGRNLMSQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L210W, T215Y | K103N | V35M, T39A, V118I, T139M, A158S, Q207K, R211N, A272P, Q278H, I293V, E297A |
| >CA34341| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMEICAELEKEGKISKIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL DKDFRKYTAFTIPSINNEMPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRKHLWNWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKHLCKLLRGTKALTEVVPLTAEAE L |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |