<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
DE02210CM006 DE02210CM006 Cameroon 2010 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    K14R, A21T, V31I, D41N, M50I, I72V, L101I, T112V, S119P, T124A, T125A, G134D, K136Q, D167E, V201I, T206S, T218S, I220L, Y227F, L234I S283G, D288N
>DE02210CM006| codons 1-288
FLDGIDKAQEEHERYHSNWRTMASDFNLPPIVAKEIVASCNKCQLKGEAIHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVKVIHTDNGPN
FTSAAVKAACWWADIQQEFGIPYNPQSQGVVESMNKELKKIIGQVREQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQISKLQNFRVYFRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDEN

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    K20R, E35N, M36I, N37D, R41K, H69K, L89M  
>DE02210CM006| codons 1-99
PQITLWQRPLVTIKIGGQLREALLDTGADDTVLENIDLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, T39K, S68G, K122E, I135T, S162C, E169D, K173A, Q174K, D177E, V189I, G196E, Q207A, R211S, V245Q, E248D, K249Q, A272P, K281R, T286A, E291D, I293V, E297K, E312D, G335D, M357R, G359S, T369V, A371V, A376V, I380V, K390R, T403M, I411M, E432D, V435I, T470A, D471E, Q480H, H483Y, L491S, L503I, K512R, S519N, Q524K, K527E, A534S, A554S  
>DE02210CM006| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICKEMEKEGKISKIGPENPYNTPV
FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFRAKNPEIVI
YQYMDDLYIGSDLEIEQHRTKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDQDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTDVVPLTKEAE
LELAENREILKDPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYARRRSA
HTNDVKQLVEVVQKIVTESVVIWGKTPKFRLPIQKETWEAWWMEYWQATWMPEWEFVNTP
PLVKLWYQLEKDPIIGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSLAETTNQKTELH
AIYLALQDSGSEVNIVTDSQYAIGIIQAQPDRSESELVNQIIEKLIEKEKVYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

References
Author Title Citation
Hora, B Genetic characterization of a panel of diverse HIV-1 isolates at seven international sites. PLoS ONE, 2015