Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA2206 | CA33273 | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | SQV | 52 |
| 2 | 3TC+AZT+IDV | 135 |
| 3 | 3TC+D4T+EFV+NFV | 78 |
| 4 | 3TC+D4T+DDI+LPV | 81 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I47V, I54V, I84V, L90M | L10F, L33F, G73C | L19I, L24M, N37H, I62V, L63P, I64V, I66V, T74S, V77I |
| >CA33273| codons 1-99 PQITLWQRPFVTIKIGGQIKEALMDTGADDTVFEEMHLPGRWKPKIVGGIGGFVKVRQYD QVPVEVCGHKAICSVLIGPTPVNVIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, M184V, L210W, T215Y | K101H | E28EA, K43Q, E44ED, V60I, V118I, K122E, I135T, T200TA, R211K, A272P, Q278H, I293V |
| >CA34290| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTAEKIKALVEICTELEQDGKISKIGPENPYNTPI FAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLHKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRAKIEELRQHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKHLCKLLRGTKALTEVVPLTEEAE L |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |