Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA14156 | CA33253 | U.S. | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+NFV | 13 |
| 2 | 3TC+D4T+NFV | 79 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46MI | G16E, L33V, M36I, P39S, I64V, I72V |
| >CA33253| codons 8-99 RPLVTIKIEGQLKEALLDTGADDTVVEEINLSGRWKPKIIGGIGGFIKVRQYDQILVEIC GHKAVGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | E28K, K32E, K101Q, G196KR, R211K, V245E, D250E, T286V |
| >CA34268| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTKEKIEALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLQKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIKQHRTKIEELRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGVKALTEVIPLTEEAE L |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |