Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 3023939 | 3023939 | U.K. | 2002 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 52 |
| 2 | AZT+DDI | 105 |
| 3 | 3TC+APV+D4T | 52 |
| 4 | D4T+DDI+EFV+LPV | 144 |
| 5 | D4T+DDI+EFV+LPV | 43 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L76V, V82F, I84C | L10I, I13V, G16E, K20I, E35D, M36I, N37NK, R41K, L63M, H69K, K70R, T74S, L89M |
| >3023939| codons 1-99 PQITLWQRPIVTVKIEGQLIEALLDTGADDTVLEDIKLPGKWKPKIIGGIGGFIKVRQYD QIMIEICGKRAIGSVVVGPTPFNCIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, K70G, L210W, T215Y | D67E | K101E, Y181C, Y188L | V8VG, T27S, V35T, T69S, W88C, K122E, D123N, I135V, S162A, K173T, Q174K, D177E, I178LM, V179M, T200A, Q207D, H221Y, L228H, V245Q, E248D, T286A, E291D, V292I, I293V, P294T, E297K, V317VA, S322T, I326V |
| >3023939| codons 1-334 PISPIETGPVKLKPGMDGPKVKQWPLSEEKIKALTEICTELEKEGKISKIGPENPYNTPV FAIKKKESSGWRKLVDFRELNKRTQDFCEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPELMI CQYMDDLLVGSDLEIGQHRAKIEELRDHLWRWGFYTPDKKYQKEPPFHWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVTLTKEAE LELAENREILKEPVHGAYYDPTKDLVAEIQKQGQ |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |