Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 01F8686 | 01F8686 | U.K. | 2002 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NVP+ EFV+ 3TC+ AZT | 24 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, I15V, M36I, R41K, I62V, L63P, I64V |
| >01F8686| codons 1-99 PQITLWQRPLVTVRVGGQLKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QVPVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K101E, G190A | K20R, V35T, T39M, K49R, V60I, V90I, K122E, D177E, I178M, T200I, Q207E, R211K, V245K, E248D, D250E, A272P, K277R, L282C, L283I, T286A, A288P, I293V, E297K, S322A | W24WC |
| >01F8686| codons 1-335 PISPIETVPVKLKPGMDGPRVKQCPLTEEKIKALTEICMEMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEMVI YQYVDDLYVASDLEIGQHRIKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIKLPDKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKCIRGAKPLTEVVPLTKEAE LELAENREILKEPVHGVYYDPAKDLIAEIQKQGQG |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |