Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| M70004 | M70004 | U.K. | 2001 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT | 2 |
| 2 | RTV+ 3TC+ AZT | 31 |
| 3 | NFV+ 3TC+ AZT | 165 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M36I, R41K, H69K, L89M, I93L |
| >M70004| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | V8VG, T27TS, V35AT, E36A, T39X, K43KE, K122E, D123DG, I135T, I142T, S162T, E169EA, K173A, D177E, I178L, V179I, I195L, T200A, Q207K, R211Q, V245K, A272P, T286V, E291D, V292I, I293V, K311R |
| >M70004| codons 1-318 PISPIETGPVKLKPGMDGPKVKQWPLSEEKIKALAAICXEMEEEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSTNNETPGTRYQYNVLPQGWKGSPAIFQTSMTKILAPFRAQNPELII YQYVDDLYVGSDLELGQHRAKIEELRKHLLQWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGVKALTDIVPLTEEAE LELAENREILREPVHGVY |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |