Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| F63925 | F63925 | U.K. | 2002 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+ 3TC+ SQV | 45 |
| 2 | NVP+ D4T+ 3TC+ SQV | 52 |
| 3 | AZT+ DDI+ ABC | 154 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, L19Q, M36I, R41K, I64V, H69Y, I72V |
| >F63925| codons 1-99 PQITLWQRPLVTVKIGGQQKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILVEICGYKAVGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, K49R, V60VI, K104KR, K122KE, I142V, A158S, D177E, I178M, T200TA, Q207E, R211K, V245E, D250E, A272P, K277R, L282C, L283I, I293V |
| >F63925| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKRSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPSIFQSSMTKILEPFRKQNPEMVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKCIRGTKALTEVVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQ |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |