Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| F65163 | F65163 | U.K. | 2002 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | SQV+ 3TC+ D4T | 43 |
| 2 | None | 54 |
| 3 | ABC+ AZT+ NVP | 14 |
| 4 | 3TC+ NVP+ ABC+ AZT | 45 |
| 5 | RTV+ SQV+ DDI+ D4T | 74 |
| 6 | 3TC+ ABC+ AZT+ TDF+ NVP | 37 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, G17GE, K20I, M36I, R41K, H69K, L89IM |
| >F65163| codons 1-99 PQITLWQRPLVTVRIGEQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNILTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, T39LS, E40ED, S162A, K173T, Q174E, T200A, Q207E, R211RK, V245T, D250E, A272P, T286TA, E291ED, V292I, I293V, P294T, S322A, I326V |
| >F65163| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICLDMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTENPDIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPITLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVTLTEEAE LELAENREILKEPVHGVYYDPAKDLVAEIQKQGQ |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |