Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| M66914 | M66914 | U.K. | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI | 65 |
| 2 | D4T+ 3TC+ NFV | 192 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46MI, N88S | I15V, K20IM, E35ED, M36I, R41RK, L63LP, I64IV, H69K, L89M, I93L |
| >M66914| codons 1-99 PQITLWQRPLVTIKVGGQLIEALLDTGADDTVLEDINLPGKWKPKIIGGIGGFIKVRQYD QIPVEICGKKAIGTVLVGPTPVNIIGRSMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V | T215V, K219Q | V21I, V35T, T39E, K43R, T69TS, K122E, D123S, I135V, K173T, Q174K, D177E, Q207E, V245Q, K249Q, A272P, T286A, E291D, V292I, I293V |
| >M66914| codons 1-333 PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICEEMEREGKISKIGPENPYNTPV FAIKKKNSSRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEIVI YQYVDDLYVGSDLEIGQHRTKIEELREHLLRWGFVTPDQKHQKEPPFLWMGYELHPDKWT VQPIQLPEQDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQG |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |