Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| F57352 | F57352 | U.K. | 2002 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI | 37 |
| 2 | DDI+ 3TC | 71 |
| 3 | D4T+ NVP+ NFV | 145 |
| 4 | ABC+ AZT+ 3TC | 62 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90LM | L10LV, I13V, I15V, K20KT, E35D, M36I, R41K, K45KQ, I62IV, H69K, T74TK, L89IM |
| >F57352| codons 1-99 PQITLWQRPVVTVKVGGQLTEALLDTGADDTVLEDINLPGKWKPQMIGGIGGFIKVRQYD QVLIEICGKKAIGKVLVGPTPVNIIGRNIMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V, T215F | K103KN | V108VI | V21I, V35T, T39N, V60I, K122E, D123N, I135T, V148VG, K173A, Q174K, D177E, T200A, Q207A, R211K, E248D, T286A, E291D, V292I, I293V, E297P |
| >F57352| codons 1-324 PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICNEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTILDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGIRYQYNGLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELRAHLLKWGFFTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPDKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVPLTPEAE LELAENREILKEPVHGVYYDPSKD |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |