Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| M92386 | M92386 | U.K. | 2001 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, I13V, I15V, G16E, K20R, E35D, M36I, R41K, K45R, R57K, L63T, H69K, L89M |
| >M92386| codons 1-99 PQITLWQRPVVTVKVEGQLREALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVKQYD QITIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E28K, K32E, V35T, V60I, D121H, K122E, I135T, K173L, Q174K, D177E, V179I, I180V, T200A, Q207A, R211S, V245K, D250E, A272P, K281R, R284K, T286A, E291D, I293V, P294T | P313PR |
| >M92386| codons 1-316 PISPIETVPVKLKPGMDGPKVKQWPLTKEKIEALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRLKNPEIIV YQYMDDLYVGSDLEIGQHRAKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIKLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLKGAKALTDVVTLTEEAE LELAENREILKERVHG |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |