Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| F26249 | F26249 | U.K. | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 283 |
| 2 | 3TC+ D4T | 128 |
| 3 | NFV+ EFV+ ABC | 41 |
| 4 | None | 48 |
| 5 | NFV+ EFV+ ABC | 62 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L89MV | T12S, L19I, K20KR, M36I, R41K, L63A, H69K, I93L |
| >F26249| codons 1-99 PQITLWQRPLVSIKIGGQIREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QIAIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K101E, Y181C, G190S | V35T, T69N, K102Q, K122E, D123G, K173T, Q174K, D177E, T200A, Q207E, V245Q, E248ED, D250E, A272P, K277R, E291D, V292I, I293V | R172RI, D218DY |
| >F26249| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSNKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEQKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFITKNPEIVI CQYMDDLYVSSDLEIGQHRAKIEELREHLLRWGFTTPYKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQG |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |