Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| F65588 | F65588 | U.K. | 2002 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ D4T | 40 |
| 2 | NFV+ DDI+ D4T | 46 |
| 3 | NVP+ DDC+ D4T | 150 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, E35D, M36I, R41K, K45R, R57K, H69K, V82I, L89M |
| >F65588| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVKQYD QILIEICGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Y181C | K11T, K20R, V21I, V35T, T39G, D123N, K173S, Q174QK, D177G, V179I, T200A, I202V, Q207A, R211S, H221Y, L228R, V245Q, E248N, A272P, T286A, E291D, I293V, P294T, E312N |
| >F65588| codons 1-334 PISPIETVPVTLKPGMDGPRIKQWPLTEEKIKALTEICGEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKNFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPGIII CQYMDDLYVGSDLEIGQHRAKVEELRAHLLSWGFTTPDKKYQKEPPFRWMGYELHPDKWT VQPIQLPNKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDVVTLTEEAE LELAENREILKNPVHGVYYDPSKDLIAEIQKQGQ |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |