Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| M60223 | M60223 | U.K. | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | RTV+ 3TC+ D4T | 26 |
| 2 | NVP+ 3TC+ D4T | 223 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, L19Q, M36I, R41K, Q61QH, L63LI, H69K, L89M, I93L |
| >M60223| codons 1-99 PQITLWQRPLVTIKVGGQQKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD HIIIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K103N | K238T | V35T, E36A, T39D, K122E, D123S, T139R, S162C, K173A, Q174R, D177E, T200A, Q207E, R211RK, V245Q, D250E, S251H, A272P, K277R, T286A, E291D, V292I |
| >M60223| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICDEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNERPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRARNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDTWT VQPIQLPEKEHWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIIPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQG |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |