Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| F61874 | F61874 | U.K. | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NVP+ IDV+ AZT+ 3TC | 82 |
| 2 | NVP+ IDV+ AZT+ 3TC | 8 |
| 3 | ABC+ DDI | 113 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L19I, M36I, N37D, R41K, D60E, H69K, L89M, I93L | G17S |
| >F61874| codons 1-99 PQITLWQRPLVTIKIGSQIKEALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYE QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, T215F | Y181C | V35T, T39D, S48T, K49R, V60I, V118I, K122E, T139R, K173T, D177E, T200A, Q207E, R211K, F214L, H221Y, V245Q, D250E, A272P, K277R, Q278N, T286A, E291D, V292I, I293V |
| >F61874| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICDELEKEGKITRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSINNERPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTQNPEIVI CQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGLFTPDKKYQKEPPFLWMGYELHPDKWT VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRNLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQG |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |