Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| F56326 | F56326 | U.K. | 2002 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+ 3TC | 117 |
| 2 | AZT+ NVP+ DDI | 54 |
| 3 | ABC+ D4T+ 3TC | 104 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, I13V, G16E, M36I, R41K, L63T, H69K, L89M |
| >F56326| codons 1-99 PQITLWQRPIVTVKIEGQLKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QITIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, L210W, T215Y | K103N | K11T, V35T, T39R, K43KE, V90I, K102KR, V118VI, D121H, K122E, I135V, S162A, K173S, D177EG, T200A, I202IV, Q207D, V245Q, A272P, L283I, I293V, E312D |
| >F56326| codons 1-334 PISPIETVPVTLKPGMDGPKVKQWPLTEEKIKALTEICRELEEEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKRNKSVTVLDVGDAYFSIPL HEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRSQNPEIVI YQYVDDLYVGSDLEIGQHRAKVEELRDHLWRWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLIRGTKALTEVVPLTEEAE LELAENREILKDPVHGVYYDPSKDLIAEIQKQGQ |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |