Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 00M3878 | 00M3878 | U.K. | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NVP+ 3TC+ D4T | 52 |
| 2 | None | 17 |
| 3 | NFV+ 3TC+ AZT | 74 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, L19IV, M36I, R41K, K43R, D60DE, Q61QE, L63P, H69K, L89M, I93L |
| >00M3878| codons 1-99 PQITLWQRPLVTIKVGGQIKEALLDTGADDTVLEEINLPGKWRPKMIGGIGGFIKVRQYE EIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K103N, Y181C | E28K, K32E, V35T, E36A, T39E, K122E, D123N, K173T, Q174K, D177E, V179I, T200A, Q207D, R211K, H221Y, V245Q, D250E, A272P, K275R, L283I, V292I, I293V | Q278G |
| >00M3878| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTKEKIEALTAICEEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEIII CQYVDDLYVGSDLEIGQHRAKIEELRDHLLKWGFTTPDKKYQKEPPFLWMGYELHPDKWT VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIRVKGLCKLIRGTKALTEIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQG |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |