Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| M50457 | M50457 | U.K. | 2002 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ NVP | 5 |
| 2 | AZT+ 3TC+ NFV | 94 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, T12S, I13V, K14KR, I15IV, K20I, E35D, M36I, N37S, R41K, K45R, H69K, A71V, L89T |
| >M50457| codons 1-99 PQITLWQRPIVSVRVGGQLIEALLDTGADDTVLEDISLPGKWKPRMIGGIGGFIKVRQYD QILIEICGKKVIGTVLVGPTPVNIIGRNTLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70KR, M184V | P4H, V35T, V60I, T107S, K122E, D123S, I135LV, K173A, Q174R, D177E, T200A, Q207A, R211S, T215X, D250E, A272P, T286A, I293V, P294T, E312D |
| >M50457| codons 1-334 PISHIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVSVLDVGDAYFSVPL DESFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRARNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELRAHLLSWGFXTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVVTLTEEAE LELAENREILKDPVHGVYYDPSKDLIAEIQKQGQ |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |