<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
M85073 M85073 U.K. 2002 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 Unknown 55
2 3TC+AZT+NFV 89

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, M36I, R41K, Q61E, H69K, T74S, L89M, I93L  
>M85073| codons 1-99
PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
EILIEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67DN, K70R, Q151M K219E Y181C, G190A   V35T, T39E, E44D, A98S, K102Q, D123N, K126KR, F171Y, K173AE, D177E, I178M, T200A, E204K, Q207E, R211K, T215X, D218DE, P243S, V245E, A272P, K281R, E291D, V292I, I293V  
>M85073| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKDGKISKIGPENPYNTPV
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKQKKSVTVLDVGDAYFSVPL
DKNFRRYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPYRAQNPEMVI
CQYMDDLYVASDLEIGQHRAKIEKLREHLLKWGFXTPEEKHQKEPPFLWMGYELHPDKWT
VQSIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGTKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQG

References
Author Title Citation
Weber, J Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005