Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| M85073 | M85073 | U.K. | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | 55 |
| 2 | 3TC+AZT+NFV | 89 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, R41K, Q61E, H69K, T74S, L89M, I93L |
| >M85073| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD EILIEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67DN, K70R, Q151M | K219E | Y181C, G190A | V35T, T39E, E44D, A98S, K102Q, D123N, K126KR, F171Y, K173AE, D177E, I178M, T200A, E204K, Q207E, R211K, T215X, D218DE, P243S, V245E, A272P, K281R, E291D, V292I, I293V |
| >M85073| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKDGKISKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKQKKSVTVLDVGDAYFSVPL DKNFRRYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPYRAQNPEMVI CQYMDDLYVASDLEIGQHRAKIEKLREHLLKWGFXTPEEKHQKEPPFLWMGYELHPDKWT VQSIELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGTKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQG |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |