Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SWC-5729 | 5729-2190 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ IDV | 33 |
| 2 | 3TC+ NFV+ D4T | 48 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N, M46L | N88D | I13V, L63P, A71T, V77I |
| >5729-2190| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADNTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD QIPIEICGHKTIGTVLIGPTPVNIIGRDLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T69T_ST, M184V, L210W, T215Y | V35M, V118I, K122E, I135T, V245Q |
| >5729-2190| codons 24-263 WPLTEEKIKALMEICTELEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKR TQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNETPGIR YQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIGQHRTKIE ELRQHLWRWGFYTPDKKHQKEPPFLWMGYELHPDKWTVQPIQLPEKDSWTVNDIQKLVGK |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |