Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SWC-5577 | 5577-1838 | U.S. | 1998 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ D4T | 76 |
| 2 | 3TC+ DDC+ IDV | 44 |
| 3 | DDC+ RTV+ SQV | 29 |
| 4 | SQV | 3 |
| 5 | DDI+ NFV+ NVP | 41 |
| 6 | DDI+ NFV+ NVP+ IDV+ 3TC+ AZT | 4 |
| 7 | NVP+ IDV+ 3TC+ AZT | 6 |
| 8 | IDV+ 3TC+ AZT | 1 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74V, M184V, L210W, T215Y | Y181C, G190A | V108I | E44X, K122E, I135V, S162C, V189I, E203D, Q207HN, R211K, V245E, E248D, K259X, A272P | F116FL |
| >5577-1838| codons 22-273 KQWPLTEEKIKALVEICTELEKDGKISKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELN KRTQDFWEVQLGIPHPAGLKKKKSVTILDVGDAYLSVPLDEDFRKYTAFTIPSVNNETPG IRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIVICQYVDDLYIASDLEIGQHRTK IDELRNHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWTVQPIELPDKDSWTVNDIQNLV GKLNWASQIYPG |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |