Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SWC-3927 | 3927-1960 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 34 |
| 2 | NRTI | 137 |
| 3 | 3TC+ RTV+ SQV | 61 |
| 4 | D4T+ NVP+ RTV+ SQV | 42 |
| 5 | 3TC+ NVP+ D4T | 24 |
| 6 | NVP+ D4T | 11 |
| 7 | NVP+ D4T+ 3TC | 24 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, L210W, T215Y | K219N | Y181V | K32X, E44D, V118I, D123E, I135T, V179I, E203K, Q207E, H208Y, R211K, K223Q, L228R, Q269X, A272P |
| >3927-1960| codons 22-273 KQWPLTEEKIXALVEICTELEKDGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELN KRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPLDKEFRKYTAFTIPSTNNETPG IRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIIIVQYVDDLYVGSDLEIGQHRTK IKELREYLWKWGFYTPDNKHQQEPPFRWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLV GKLNWASHIYPG |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |