Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SWC-3714 | 3714-119 | U.S. | 1996 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT | 8 |
| 2 | AZT+ 3TC+ RTV | 10 |
| 3 | AZT+ 3TC+ RTV+ IDV | 26 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| E35D, R41K, L63P, H69K, A71T, I93L, C95F |
| >3714-119| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEDMNLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGKKTIGTVLVGPTPVNIIGRNLLTQLGFTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V, L210W, T215Y | E44X, I135V, S162C, I178M, T200A, Q207E, R211K, A272P |
| >3714-119| codons 42-273 EKDGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLK KKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQ CSMTKILEPFRKQNPDMVIYQYVDDLYVGSDLEIGQHRAKIEELREHLWKWGFYTPDKKH QKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPG |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |