Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SWC-2551 | 2551-3137 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | NA |
| 2 | 3TC+ NFV+ D4T | 24 |
| 3 | DDI+ ABC+ APV | 37 |
| 4 | ABC+ APV | 1 |
| 5 | ABC+ APV+ 3TC+ AZT | 6 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54L, L90M | L33LF, G73S | L10I, K20R, E35D, M36I, N37T, I62V, L63P, A71V |
| >2551-3137| codons 1-92 PQITLWQRPIVTIKIGGQLREALLDTGADDTVFEDITLPGRWKPKMIGGIGGFLKVRQYD QVPIEICGHKVISTVLVGPTPVNIIGRNLMTQ |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V, T215F | K219Q | V60I, I135L, G196E, T200A, I202V, R211RK, V245K |
| >2551-3137| codons 32-260 KALVEICTEMEKEGKISKIGPENPYNTPIFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQ LGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSLNNETPGIRYQYNVLPQ GWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIEQHRAKVEELRQHLLK WGFFTPDQKHQKEPPFLWMGYELHPDKWTVQPIKLPEKDSWTVNDIQKL |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |