Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SWC-2551 | 2551-2223 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | NA |
| 2 | 3TC+ NFV+ D4T | 20 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | G73S | L10I, K20R, E35D, M36I, L63P, A71V, V77I, I93L | Q92QLPR |
| >2551-2223| codons 1-99 PQITLWQRPIVTIKIGGQLREALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKVISTVLIGPTPVNIIGRNLMTRLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V, T215F | K219Q | V60I, I135L, G196E, T200A, I202V, R211K, V245K, A272P |
| >2551-2223| codons 23-273 QWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPIFAIKKKNSTRWRKLVDFRELNK RTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSLNNETPGI RYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIEQHRAKV EELRQHLLKWGFFTPDQKHQKEPPFLWMGYELHPDKWTVQPIKLPEKDSWTVNDIQKLVG KLNWASQIYPG |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. | J Infect Dis, 2005 |