Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SWC-0233 | 0233-2198 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI+ EFV+ NFV | 12 |
| 2 | NFV | 8 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82T, L90M | L10V, K20R, M36I, L63P, A71V, I72V, I93L |
| >0233-2198| codons 1-99 PQITLWQRPVVTIKIGGQLREALLDTGADDTVLEEINLPGRWKPKIIGGIGGFVKVRQYD QIPIEICGHKVVGTVLVGPTPTNIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, L74V, M184V, L210W, T215Y | L100I, K103N | K43N, K122E, D123E, V189I, I202V, Q207G, R211K, L228Q, A272P |
| >0233-2198| codons 29-273 EKIKALVEICTELENEGKISKIGPENPYNTPVFAIKKKNSDKWRKVVDFRELNKRTQDFW EVQLGIPHPAGIKKNKSVTVLDVGDAYFSVPLDEEFRKYTAFTIPSINNETPGIRYQYNV LPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYVDDLYIGSDLEIGQHRTKVEELRGH LWKWGFYTPDKKHQKEPPFQWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWAS QIYPG |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |