Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| M41984 | M41984 | U.K. | 2002 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 43 |
| 2 | None | 168 |
| 3 | D4T+ 3TC+ IDV | 139 |
| 4 | DDI+ EFV+ AZT+ 3TC | 137 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, V75M, M184V, L210W, T215Y | K219E | K103N, Y181C | V108I | V35T, V60I, K122E, D123S, I135T, K173S, Q174K, V179I, T200A, E203K, Q207D, R211K, D218E, H221Y, L228H, V245Q, D250E, A272T, E291D, V292I, I293V |
| >M41984| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEKEGKISKIGPENPYNTPI FAIKKKNSTRWRKLMDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTILDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPDIII CQYVDDLYVGSDLEIGQHRAKIKELRDHLWKWGFYTPEEKYQKEPPFHWMGYELHPDKWT VQPIQLPEKESWTVNDIQKLVGKLNWASQIYTGIKVKQLCKLLRGTKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L33F | I13V, K14R, E35D, M36I, R41K, K43KR, R57K, H69K, L89M |
| >M41984| codons 1-99 PQITLWQRPLVTVRIGGQLKEALLDTGADDTVFEDINLPGKWRPKMIGGIGGFIKVKQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |