Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| F62040 | F62040 | U.K. | 2001 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ D4T | 89 |
| 2 | NVP+ 3TC+ D4T | 19 |
| 3 | NFV+ 3TC+ AZT | 110 |
| 4 | AZT+ ABC+ NFV+ 3TC | 4 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, T12X, I15V, K20R, E35D, M36I, R41K, R57K, D60E, I62V, L63T, L89M |
| >F62040| codons 1-99 PQITLWQRPVVXIKVGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYE QVTIEICGHKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K20R, V35T, T39TA, E40D, V60I, K64KR, I135T, E138EA, I142IT, S162H, K173IT, Q174K, I178IV, I202V, Q207E, R211EK, F214L, V245K, A272P, E291D, V292I, I293V, P294Q, E297T |
| >F62040| codons 1-312 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICADMEKEGKISKIGPENPYNTPI FAIRKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSTNNATPGTRYQYNVLPQGWKGSPAIFQHSMTKILEPFRIKNPDVVI YQYMDDLYVGSDLEIGQHRTKVEELREHLLEWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDIVQLTTEAE LELAENREILKE |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |