<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
M47502 M47502 U.K. 2002 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 NVP+ 3TC+ AZT 118
2 DDI+ D4T+ NFV 51

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
N88NS   L10I, I13V, K20KT, E35ED, M36I, R41K, L63T, I64IV, H69K, L89M  
>M47502| codons 1-99
PQITLWQRPIVTVKIGGQLTEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QITVEICGKKAIGTVLVGPTPVNIIGRSMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    Y181YC   K11T, K20KR, V35T, K122E, D123X, T139TR, K173S, T200A, I202V, Q207D, T215X, Q242QH, V245Q, E248D, D250E, A272P, V276VI, K277KR, T286A, I293V, E312D, I326V I159IL
>M47502| codons 1-334
PISPIETVPVTLKPGMDGPRVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEXFRKYTAFTIPSINNERPGIRYQYNVLPQGWKGSPALFQSSMTKILEPFRSQNPDIVI
CQYMDDLYVGSDLEIGQHRAKVEELRDHLLRWGFXTPDKKHQKEPPFLWMGYELHPDKWT
VHPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKIRQLCKLLRGAKALTEVVPLTEEAE
LELAENREILKDPVHGVYYDPSKDLVAEIQKQGQ

References
Author Title Citation
Weber, J Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005