Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| M47502 | M47502 | U.K. | 2002 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NVP+ 3TC+ AZT | 118 |
| 2 | DDI+ D4T+ NFV | 51 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| N88NS | L10I, I13V, K20KT, E35ED, M36I, R41K, L63T, I64IV, H69K, L89M |
| >M47502| codons 1-99 PQITLWQRPIVTVKIGGQLTEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QITVEICGKKAIGTVLVGPTPVNIIGRSMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Y181YC | K11T, K20KR, V35T, K122E, D123X, T139TR, K173S, T200A, I202V, Q207D, T215X, Q242QH, V245Q, E248D, D250E, A272P, V276VI, K277KR, T286A, I293V, E312D, I326V | I159IL |
| >M47502| codons 1-334 PISPIETVPVTLKPGMDGPRVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEXFRKYTAFTIPSINNERPGIRYQYNVLPQGWKGSPALFQSSMTKILEPFRSQNPDIVI CQYMDDLYVGSDLEIGQHRAKVEELRDHLLRWGFXTPDKKHQKEPPFLWMGYELHPDKWT VHPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKIRQLCKLLRGAKALTEVVPLTEEAE LELAENREILKDPVHGVYYDPSKDLVAEIQKQGQ |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |