Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| F78596 | F78596 | U.K. | 2002 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | IDV+ D4T+ DDI | 18 |
| 2 | D4T+ DDI | 38 |
| 3 | DDI | 3 |
| 4 | None | 6 |
| 5 | NVP+ ABC+ AZT | 74 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67DN, T215F | G190A | V35R, V60I, K122E, D123N, I135T, V148VG, K173S, V179I, T200A, Q207A, R211S, L228LR, V245Q, D250E, S251N, A272P, E291D, I293V, P294T, E297A, K311R, E312D |
| >F78596| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALREICTELEKEGKISKIGPENPYNTPI FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGIRYQYNGLPQGWKGSPAIFQSSMTKILEPFRSQNPDIII YQYMDDLYVASDLEIGQHRAKIEELRAHLLSWGFFTPDKKHQKEPPFRWMGYELHPDKWT VQPIQLPEKENWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDVVTLTAEAE LELAENREILRDPVHGVYYDPSKDLIAEIQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10I, I13V, I15L, K20I, E35D, M36I, L63S, H69K, L89M |
| >F78596| codons 1-99 PQITLWQRPIVTVKLGGQLIEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVRQYD QISIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |