<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
F30020 F30020-1 U.K. 2002 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 3TC+DDI+NVP 1

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        E6DN, K11KQ, M16MT, E28EA, V35T, T39TS, V60I, V118I, K122E, D123N, I135T, K173S, Q174K, D177E, I178L, V179I, T200A, Q207E, R211K, F214L, V245Q, D250E, A272P, T286A, E291D, I293V, P294A L34LS, C38CF
>F30020-1| codons 1-299
PISPIDTVPVQLKPGTDGPKVKQWPLTAEKIKASTEIFSEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPELII
YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDVVALTEEA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, I15IV, E34ED, E35D, M36I, R41K, R57K, H69K, L89M V56VE
>F30020-1| codons 2-99
QITLWQRPLVTVRVGGQLKEALLDTGADDTVLDDINLPGKWKPKMIGGIGGFIKEKQYDQ
ILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Weber, J Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005