Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| F56949 | F56949 | U.K. | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDC | 58 |
| 2 | None | 40 |
| 3 | DDI+ D4T+ NFV | 154 |
| 4 | TDF+ DDI+ D4T | 43 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L210W, T215Y | V21I, V35T, E36A, T39E, S48T, V118I, K122E, D123G, K173A, D177E, T200A, Q207E, R211K, V245Q, A272P, I274V, Q278H, K281R, T286A, E291D, V292I, I293V, K311R |
| >F56949| codons 1-333 PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTAICEELEKEGKITKIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELREHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGVKVKHLCRLLRGAKALTDIVPLTEEAE LELAENREILREPVHGVYYDPSKDLIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | T12S, I13V, I15V, L19I, K20T, M36I, R41K, K45T, L63P, H69K, I93L |
| >F56949| codons 1-99 PQITLWQRPLVSVKVGGQITEALLDTGADNTVLEEINLPGKWKPTMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |