<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
M60223 M60223 U.K. 2002 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 RTV+ 3TC+ D4T 26
2 NVP+ 3TC+ D4T 223

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K103N K238T V35T, E36A, T39D, K122E, D123S, T139R, S162C, K173A, Q174R, D177E, T200A, Q207E, R211RK, V245Q, D250E, S251H, A272P, K277R, T286A, E291D, V292I  
>M60223| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICDEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNERPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRARNPEIVI
YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDTWT
VQPIQLPEKEHWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIIPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, L19Q, M36I, R41K, Q61QH, L63LI, H69K, L89M, I93L  
>M60223| codons 1-99
PQITLWQRPLVTIKVGGQQKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
HIIIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Weber, J Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005