Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| F51354 | F51354 | U.K. | 2002 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 30 |
| 2 | None | 152 |
| 3 | 3TC+ AZT | 38 |
| 4 | AZT+ SQV+ 3TC+ DDC | 36 |
| 5 | D4T+ NFV+ NVP | 79 |
| 6 | None | 11 |
| 7 | DDI+ D4T+ EFV | 109 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67DN, K70KR, L74LV, T215F | K103N, Y181C | A98G | K11T, K20R, V21I, V35T, T39L, T69X, V106I, D123N, I135L, D177E, I178L, V179I, T200A, I202V, Q207A, R211X, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, P294T, E312G | N57NI |
| >F51354| codons 1-334 PISPIETVPVTLKPGMDGPRIKQWPLTEEKIKALTEICLEMEKEGKISKIGPENPYITPV FAIKKKNSXRWRKVVDFRELNKRTQDFWEVQLGIPHPGGLKKNKSITVLDVGDAYFSVPL DKNFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPELII CQYMDDLYVGSDLEIGQHRAKVEELRAHLLXWGFFTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVTLTEEAE LELAENREILKGPVHGVYYDPSKDLIAEIQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, I13V, K14R, G16E, K20T, E35D, M36I, R41K, R57K, L63T, H69K, I72T, T74TA, L89M |
| >F51354| codons 1-99 PQITLWQRPVVTVRIEGQLTEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QITIEICGKKATGAVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |