Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| M49551 | M49551 | U.K. | 2001 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDC | 34 |
| 2 | D4T+ NVP+ 3TC | 146 |
| 3 | RTV+ ABC+ DDI+ AZT | 96 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, T215FI | K219Q | K11T, K20R, V21I, V35T, T39E, K64KN, D67X, T69N, D121H, K122E, D123S, K173L, D177E, V179I, I202V, Q207A, R211KN, F214FL, V245Q, E248N, S251C, I293V | E291V |
| >M49551| codons 1-297 PISPIETVPVTLKPGMDGPRIKQWPLTEEKIKALTEICEEMEKEGKISKIGPENPYNTPV FAINKKXSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL HESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRLQNPEIII YQYMDDLYVGSDLEIGQHRTKVEELRAHLLKWGLFTPDQKHQKEPPFLWMGYELHPDKWT VQPIQLPNKDCWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTVVVPLTE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T4TP, I13V, G16E, E35D, M36I, R41K, H69K, L89M |
| >M49551| codons 1-99 PQIPLWQRPLVTVKIEGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |